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Insufficient human clinical trials have led to a lack of data to determine a safe dose

Plimmer (1912) [1908]

This consistency allows researchers to work with greater confidence when conducting repeatable and structured experiments

Third, Dr Dean Jones uses real science more heavily than Trevor, but his mechanistic confidence often exceeds what the human evidence can support

DOI: 10.1007/s11095-009-0045-6 United States Pharmacopeia

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